Epigenetic: The genetic mechanism that affects cell degeneration and aging. Revealing the 3 main process mechanisms and how to take care of your health to stay away from dangerous diseases!

Epigenetics is a mechanism that controls gene expression independent of changes in the genetic material, while genes or genetic material (Deoxyribonucleic acid, DNA) are the key factors that determine human characteristics through the production of proteins.

Genetic conditions can be triggered or suppressed by various environmental factors such as diet, stress, pollution, and lifestyle. In comparison to human life, สนใจสมัคร? คลิกที่นี่เพื่อเริ่มต้น genes can be said to be the destiny of each person, which is received from birth.

Supergenetics can be compared to karma or lifestyle that can change the fate or expression of genes.  Both healthy and unhealthy lifestyles can change the expression of genes without changing the sequence of the genetic material. The nature of supergenetics has led to the knowledge that people who carry a disease-causing gene do not necessarily have symptoms of the disease if the disease-causing gene is not expressed, and that supergenetics can be passed on to the next generation.

Main Epigenetic Mechanisms

Epigenetics works through three main processes:

DNA Methylation 

The addition of methyl groups (CH3) to DNA causes gene expression to decrease or inactivate certain genes. This process is one of the important ways cells can control whether genes are activated or inactive.

Histone Modification 

Human DNA is packaged in the cell nucleus around proteins called histones. When these proteins are modified with chemical groups such as acetyl or methyl, they can make it easier or harder for genes to be read.

Non-coding RNA Regulation 

In our body, there are many types of RNA that do not make proteins but control gene expression, such as microRNA that can turn off or inhibit the function of certain genes.

Epigenetic influences on health

• Epigenetic cancer  is involved in cancer pathogenesis because abnormalities in DNA methylation and histone modification can activate or deactivate cancer-related genes, such as turning off tumor suppressor genes or activating oncogenes.
• Metabolic diseases such as diabetes and obesity.  Eating habits high in sugar and fat can cause epigenetic changes that cause the cells that control blood sugar to malfunction, increasing the risk of developing type 2 diabetes and obesity.
• Behavior and psychiatric conditions.  Studies have shown that epigenetics can affect behavior and mood. For example, chronic stress can cause changes in DNA methylation in genes that control the hormone cortisol, making you more likely to suffer from depression or anxiety.
• Effects on the fetus  The mother’s environment during pregnancy, such as nutrition, stress or pollution, can affect the baby’s epigenetics, increasing the risk of chronic diseases later in life.

Epigenetics and inheritance

Epigenetics is interesting in that it can be passed down from generation to generation. For example, animal studies have shown that if parents have poor diets, this can affect the health of their offspring, even if they do not directly inherit the mutated genes.

Epigenetic care for good health

• Good nutrition, consuming foods high in antioxidants, such as vegetables and fruits, can help prevent unwanted epigenetic changes.
• Exercise reduces stress and activates genes involved in energy metabolism.
• Stress management, meditation and relaxation training can reduce the epigenetic effects of stress hormones.
• Avoid toxins. Environmental pollutants such as cigarette smoke and certain chemicals can negatively affect epigenetics.

Epigenetics is the study of how genes are expressed without altering the DNA sequence, which has implications for health, behavior, and disease. Although epigenetics is influenced by the environment, we can take care of and change our behavior to have a positive impact on our health and that of our children in the long run.